rb cst 9309 (Cell Signaling Technology Inc)

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Cell Signaling Technology Inc rb cst 9309
Rb Cst 9309, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 708 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rb+cst+9309/Phospho-Rb+(Ser807%2F811)+XP+Rabbit+mAb/pmc12992861-64-6-7
Average 96 stars, based on 708 article reviews

rb cst 9309 - by Bioz Stars, 2026-10

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Article Title: Oral estrogen receptor PROTAC® vepdegestrant (ARV-471) is highly efficacious as monotherapy and in combination with CDK4/6 or PI3K/mTOR pathway inhibitors in preclinical ER+ breast cancer models
Article Snippet: Antibodies used against the following targets were acquired from Cell Signaling Technologies (CST); GSPT1 (CST-14980S), Aiolos (CST-15103S), IKZF1/IKAROS (CST-5443S), CK1α (CST-2655S), AKT (CST-9272), phospho-Akt (Ser473) (CST-4060), Rb (CST-9309), phospho-Rb (Ser780) (CST-9307), S6 ribosomal protein (CST-2217), phospho-S6 ribosomal protein (Ser235/236) (CST4857) and progesterone receptor (PGR-A, -B, CST-8757).

Article Title: TFAP2C-DDR1 axis regulates resistance to CDK4/6 inhibitor in breast cancer.
Article Snippet: Breast cancer is the predominant malignancy with the majority of cases are characterized as HR+/HER2-subtype.. Although cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) have shown remarkable efficacy in treating this subtype when combined with endocrine therapy, the development of resistance to these inhibitors remains a significant clinical obstacle.. Hence, there is an urgent need to explore innovative therapies and decipher the underlying mechanisms of resistance to CDK4/6i.

Article Title: Oral Estrogen Receptor PROTAC Vepdegestrant (ARV-471) Is Highly Efficacious as Monotherapy and in Combination with CDK4/6 or PI3K/mTOR Pathway Inhibitors in Preclinical ER+ Breast Cancer Models
Article Snippet: Antibodies used against the following targets were acquired from Cell Signaling Technologies (CST); ERα (D8H8, CST-8644), β- Actin (D6A8, CST-8457) GSPT1 (CST14980S), Aiolos (CST-15103S), IKZF1/IKAROS (CST-5443S), CK1α (CST-2655S), AKT (CST-9272), phosphoAkt (Ser473) (CST-4060), Rb (CST-9309), phospho-Rb (Ser780) (CST-9307), S6 ribosomal protein (CST2217), phospho-S6 ribosomal protein (Ser235/236) (CST-4857) and progesterone receptor (PGR-A, -B, CST-8757).

Article Title: Supporting Information for EHMT2-mediated transcriptional reprogramming drives neuroendocrine transformation in non-small cell lung cancer
Article Snippet: Primary antibodies used in this study were EHMT2 (CST, #68851), EGFR (Santa Cruz, sc373746), RB (CST, #9309), YAP (CST, #14074), p-YAP (CST, #13008), H3K9me2 (CST, #4658), Histone3 (CST, #4499), β-catenin (CST, #8480), p70S6K (CST, #2708), p-p70S6K (CST, #9234), SMAD2 (CST, #5339), p-SMAD2 (CST, #18338), SMAD3 (CST, #9523), p-SMAD3 (CST, #9520), SFRP1 (CST, #3534), β-actin (Santa Cruz, sc-47778), CHGA (Abcam, 254557).

Article Title: B3GNT3 facilitates NFKB2 processing and non-canonical NF-κB activation to drive lung adenocarcinoma progression
Article Snippet: Antibodies against pRB (s807/811, CST, 8516), Rb (CST, 9309) and p100 (s866/870, CST, 4810), p100 (CST, 4882) and H3 (CST, 9715) were purchased from Cell Signaling Tech.

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Article Title: A novel selenium analog of HDACi-based twin drug induces apoptosis and cell cycle arrest via CDC25A to improve prostate cancer therapy.
Article Snippet: The protein samples were separated on acrylamide gels and then transferred onto a PVDF membrane (Millipore, R1DB89779) using a transfer buffer (20% methanol). .. The protein samples were detected by immunoblotting with Ki67 (CST, 2586), PCNA (Bioss, bs-2007R), CDK2 (Santa Cruz Biotechnology, sc-6248), CDK4 (Santa Cruz Biotechnology, sc-23896), CDK6 (Abways, CY5835), cyclin D (CST, 55506), cyclin E (Sino Biological Inc., 10902-RP02), Rb (CST, 9309), p-Rb (CST, 8516), Ac-H3 (CST, 8173), tubulin (CST, 5335), cleaved-PARP (c-PARP) (CST, 5625), Bcl-2 (CST, 15071), Bax (CST, 89477), p21 (ZENBIO, 382492), cleaved-caspase3 (c-Casp3) (CST, 9664), ZEB1 (CST, 70512), E-cadherin (CST, 14472), vimentin (CST, 5741), p-PDH (Abcam, ab177461), HDAC1/2/3/5/6/7/8 (Immunoway) , and CDC25A (CST, 3652) antibodies. .. Using tubulin as a control, band strength was evaluated using ImageJ software.

Article Title: Mitotic CDK4/6 activity sustains spindle checkpoint signalling to prevent mitotic slippage and genomic instability
Article Snippet: .. Antibodies used for Western blotting included phospho-Rb (CST #8180), Rb (CST #9309), β-Tubulin (ABclonal A12289), BubR1 (Abclonal A1775), Cdc27 (Abcam Ab10538), Cyclin B1 (Santa Cruz sc-245), Cyclin D1 (Santa Cruz sc-8396), GAPDH (Abcam 9484), KNL1 (Abcam ab70537), CDH1/FZR1 (Santa Cruz sc-166714), Mps1/TTK (Abclonal A2500 ), CDK4 (Santa Cruz sc-23896), CDK6 (Santa Cruz sc-7961), phospho-KNL1 MELT (CST #40758), thiophosphate ester (Abcam ab92570), and HRP-conjugated His-tag antibodies (Abclonal AE104). .. Species-specific HRP-conjugated secondary antibodies (Thermo Fisher) were used at 1:10,000.

Article Title: PI3K inhibitor idelalisib enhances the anti-tumor effects of CDK4/6 inhibitor palbociclib via PLK1 in B-cell lymphoma.
Article Snippet: In Situ Cell Death Detection Kit (Roche, Basel, Switzerland, #12156792910) was used to detect in situ apoptosis. .. In western blotting (WB) detection, antibodies against PI3K p110δ (Abcam, MA, USA, #ab302958), Phospho-Ser473AKT (CST, #9271), AKT (CST, #4691), Phospho-Ser2448-mTOR (CST, #2971), mTOR (CST, #2972), Active forms of poly-ADP ribose polymerase (Cleaved PARP, CST, #9532), Cleaved-caspase3 (CST, #9664), Caspase8 (CST, #9746), BCL2 antagonist/killer (BAK, CST, #12105), BCL-2 (CST, #2870), BCL-xL (CST, #2764), X-linked inhibitor of apoptosis protein (XIAP, CST, #2045), MCL-1 (CST, #5453), Rb (CST, #9309), Phospho-Ser807/811-Rb (CST, #8516), CDK4 (CST, #12790), CDK6 (CST, #13331), Cyclin D1 (CST, #2978), cell division cyclerelated protein 2 (CDC2, CST, #9116), Phospho-Try15-CDC2 (CST, #4539), CDK2 (CST, #2546), Cyclin B1 (CST, #12231), Cyclin A (CST, #4656), PLK1 (CST, #4513), CDC25A (Affinity Biosciences, OH, USA, #AF6252), β-Actin (CST, #3700) were used. ..

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